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セマグルチドが非DM肥満CKDでアルブミン尿減少

Semaglutide in patients with overweight or obesity and chronic kidney disease without diabetes: a randomized double-blind placebo-controlled clinical trial. Nat Med. 2024 Oct 25. doi: 10.1038/s41591-024-03327-6. Epub ahead of print. PMID: 39455729.

24/10/25

Nat Med

介入試験

非DM肥満CKD101人
(eGFR≧25、UACR 30-3500、BMI≧27)

セマグルチド2.4mg/週 vs プラセボ24週で
UACRは-52.1%減少(-65.5 - -33.4)

肥満非DMのCKDでアルブミン尿の減少

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